SCNN1B Rabbit pAb

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the beta subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), and Liddle syndrome. Synonyma: BESC1, ENaCb, SCNEB, LIDLS1, PHA1B2, ENaCbeta, beta-ENaC, beta-NaCH, SCNN1B