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ULK1/ULK2 Rabbit pAb

ULK1/ULK2 Rabbit pAb
Poznámka k dopravě
Dopravné k jednorázové objednávce činí 2.000 Kč, které rozpočítáváme při fakturaci do cen za zboží. V rámci snížení nákladů na dopravu se snažíme konsolidovat objednávky tak, aby se tato suma rozdělila mezi maximum zákazníků. Před objednáním u dodavatele jsou všichni zákazníci vždy předem informovaní o aktuální výši dopravy.
ULK1/ULK2 Rabbit pAb
Mammalian ULK1 (unc-51 like kinase 1) and ULK2, Caenorhabditis elegans UNC-51, and Drosophila melano...
3 136,00Kč
Cena bez DPH: 2 591,74Kč
  • Výrobce: ABclonal
  • Kód výrobce: ABC-A18685

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Dotaz na zboží

Mgr. Lenka Šídová (Kasalová)

Produktový specialista - Buněčná biologie (ext.)

Mammalian ULK1 (unc-51 like kinase 1) and ULK2, Caenorhabditis elegans UNC-51, and Drosophila melanogaster Atg1 are serine/threonine kinases that regulate flux through the autophagy pathway in response to various types of cellular stress.ULK1 and ULK2 all have different tissue-specific expressions partially contributing to diverse and ULK-specific interaction networks in various tissues.ULK1 (or its close family member ULK2) interacts with several other proteins to form a large complex that is required for the formation of an autophagosome. The other proteins that complex with ULK1/ULK2 include ATG13, ATG101, and RB1CC1 (FIP200/ATG17).AMPK, activated during low nutrient conditions, directly phophorylates ULK1 at multiple sites including Ser317, Ser555, and Ser777. Conversely, mTOR, which is a regulator of cell growth and is an inhibitor of autophagy, phosphorylates ULK1 at Ser757 and disrupts the interaction between ULK1 and AMPK. Synonyma:
Technické specifikace
Doprava a skladování Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Vlastnosti
Aplikace WB,ELISA
Klon Polyclonal Antibodies
Předpokládaná křížová reaktivita Human
Původ Rabbit
Specifita Human
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