RELA Rabbit pAb

Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific, actinin binding activity, and ankyrin repeat binding activity. Involved in several processes, including negative regulation of protein sumoylation, postsynapse to nucleus signaling pathway, and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including cellular response to hepatocyte growth factor stimulus, cellular response to lipopolysaccharide, and positive regulation of interleukin-12 production. Located in several cellular components, including chromatin, cytosol, and glutamatergic synapse. Is expressed in several structures, including alimentary system, early conceptus, genitourinary system, musculature, and skin. Human ortholog(s) of this gene implicated in ductal carcinoma in situ, lung non-small cell carcinoma, lymphoma, and renal cell carcinoma. Orthologous to human RELA (RELA proto-oncogene, NF-kB subunit). Synonyma: p65, p65 NFkB, p65 NF-kappa B, RELA