PE Rabbit anti-Mouse CD140b/PDGFR beta mAb

Enables platelet-derived growth factor-activated receptor activity and signaling receptor binding activity. Involved in several processes, including positive regulation of intracellular signal transduction, protein phosphorylation, and vasculature development. Acts upstream of or within several processes, including animal organ development, response to ceramide, and ruffle assembly. Located in cell surface, cytoplasm, and ruffle. Is expressed in several structures, including alimentary system, extraembryonic component, genitourinary system, nervous system, and sensory organ. Used to study basal ganglia calcification, infantile myofibromatosis, myeloproliferative neoplasm, and severe nonproliferative diabetic retinopathy. Human ortholog(s) of this gene implicated in basal ganglia calcification, glioblastoma, infantile myofibromatosis, myeloproliferative neoplasm (multiple), and renal cell carcinoma. Orthologous to human PDGFRB (platelet derived growth factor receptor beta). Synonyma: Pdgfr, CD140b, PDGFR-1