Phospho-Camk2-T286 Rabbit mAb

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2 )/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. Synonyma: CAMKA, MRD53, MRT63, CaMKIIalpha, CaMKIINalpha, CAM2, CAMK2, CAMKB, MRD54, CaMKIIbeta, CAMKD, CAMK, CAMKG, MRD59, CAMK-II, Phospho-Camk2-T286