Phospho-YWHAZ -Ser58+YWHAH -Ser59+YWHAG-Ser59+YWHAB -Ser60 Rabbit mAb

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. Synonyma: HEL4, YWHAD, KCIP-1, HEL-S-3, POPCHAS, HEL-S-93, 14-3-3-zeta,YWHA1,14-3-3GAMMA, DEE56, EIEE56,PPP1R170,GW128,HEL-S-1,HS1,KCIP-1,YWHAA,