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INS-1 Cells

INS-1 Cells
INS-1 Cells
The INS-1 cell line is derived from an x-ray-created transplantable insulinoma in rats. Because INS-...
17 303,00Kč
Cena bez DPH: 14 300,00Kč
  • Výrobce: Cytion
  • Kód výrobce: CYT-300471

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Dotaz na zboží
The INS-1 cell line is derived from an x-ray-created transplantable insulinoma in rats. Because INS-1 cells contain a high concentration of insulin and respond to changes in glucose levels, they are frequently used to study the function of beta cells. Growth and hormone expression are dependent on the reducing agent 2-mercaptoethanol. INS-1 cells are notable for their heterogeneity, consisting of mature insulin-positive cells and immature bi-hormonal cells expressing insulin and glucagon proteins. Bi-hormonal INS-1 cells have lower Nkx6.1 expression and lack alpha cell markers, indicating they are not fully matured. Furthermore, chronic glucose stimulation reduces insulin gene and protein expression in INS-1 cells. As such, insulin and proglucagon-derived peptides like GLP-1, GLP-2, and glucagon levels are reduced. Rat cell lines, Pancreas, islets of Langerhans, Rat insulinoma, Growth Conditions: Adherent/suspension, Biosafety level: BSL 1
Technické specifikace
Doprava a skladování Adherent/suspension
Poznámka k dopravě Dopravné k objednávce je závislé na BLS třídě dodávaných produktů a na konkrétních podmínkách přepravy. Před objednáním nás prosím kontaktujte a naši pracovníci Vám vždy cenu dopravy vyčíslí pro každý jednotlivý případ. Každá viála obsahuje celkem přibližně 3 miliony adherentních buněk nebo 5 milionů suspenzních buněk s typickou životaschopností po rozmrazení v rozmezí 80-95 %. Tyto údaje slouží jako obecné vodítko; ačkoli dodržujeme přísné normy kvality, přesné počty buněk a životaschopnost se mohou lot-to-lot lišit a nejsou zaručeny.
Vlastnosti
Původ Rat
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