[KO Validated] IFNAR2 Rabbit pAb

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family. Mutations in this gene are associated with Immunodeficiency 45. Synonyma: IFN-R, IMD45, IFNABR, IFNARB, IFN-R-2, IFN-alpha-REC, R2