ABflo® 647 Rabbit anti-Mouse CD366 (TIM-3) mAb

Predicted to enable metal ion binding activity. Involved in several processes, including regulation of cytokine production, regulation of leukocyte activation, and toll-like receptor signaling pathway. Located in cell surface, early endosome, and immunological synapse. Is expressed in several structures, including dorsal aorta, gut, liver, lung, and reproductive system. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and renal cell carcinoma. Orthologous to human HAVCR2 (hepatitis A virus cellular receptor 2). Synonyma: Tim3, TIM-3, Timd3