ABflo® 488 Rabbit anti-Mouse IL22 mAb

Enables cytokine activity. Involved in negative regulation of inflammatory response. Acts upstream of or within positive regulation of transcription by RNA polymerase II, reactive oxygen species metabolic process, and regulation of tyrosine phosphorylation of STAT protein. Is active in extracellular space. Is expressed in ileum, retina, and skin. Used to study liposarcoma. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL22 (interleukin 22). Synonyma: IL-22, If2b1, Iltif, IL-22a, ILTIFa