eIF2B epsilon (EIF2B5) Rabbit mAb

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. Synonyma: CLE, CACH, LVWM, EIF-2B, EIF2Bepsilon, eIF2B epsilon (EIF2B5)