abberior CELL LINE- Mito-SNAP / ER-Halo

abberior CELL LINES are designed to simplify and enhance advanced fluorescence microscopy. By integrating specific labeling systems like SNAP- and Halo-tags, these cell lines enable precise, reproducible, and non-invasive visualization of key cellular structures in real time. They are ideal for testing new fluorescent probes, optimizing imaging protocols, and benchmarking high-end microscopy systems. The abberior CELL LINE, Mito-SNAP / ER-Halo is a genetically modified osteosarcoma cell line derived from the human U2OS parental cell line. It has been engineered to incorporate a SNAP-Tag at a mitochondria-specific gene and a Halo-Tag at an ER-specific gene, enabling two-color visualization of both organelles in living cells. Since the abberior CELL, Organelle 2-Color retains the characteristics of the parental U2OS cell line, including high genetic stability and ease of culture, the SNAP-Halo-Tag system allows users to selectively and rapidly label mitochondria and ER. This cell line has been vigorously tested and is highly compatible with the abberior LIVE probes (SNAP-, Halo-, HaloX-ligands) and direct labels (actin, tubulin, DNA, Mito, membrane), making it well-suited for precise and efficient staining in live-cell imaging applications. As a result, this cell line provides a robust platform for real-time organelle imaging in both normal and disease-related conditions, thereby contributing significantly to the fields of fundamental research and applied biomedical studies. Please refer to our product sheet for detailed instructions on the characteristics, handling, and storage. Each cell line is delivered with a 2 nmol of abberior LIVE 590 SNAP and abberior LIVE RED Halo, allowing you to start your experiments right away.

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