CD45 iFluor488

The clone 2D1, a mouse monoclonal antibody, recognizes a hematopoietic cell surface glycoprotein antigen with a molecular weight of 180-220 kDa known as CD45. It is present on all human leukocytes including lymphocytes, monocytes, granulocytes, eosinophils, and basophils in peripheral blood. CD45 has a role in signal transduction, modifying signals from other surface molecules. 2D1 has been reported to react weakly with mature circulating erythrocytes and platelets. The antibody also recognizes the human leukocyte common antigen found on cells from spleen, lymph nodes, bone marrow cells and granulocytes.