FCGR2B Rabbit pAb

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. Synonyma: CD32, FCG2, CD32B, FCGR2, IGFR2, FCGR2C, FcGRIIB, FcRII-c, FcgammaRIIb, FCGR2B