ZMPSTE24 Rabbit pAb

This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. Synonyma: HGPS, PRO1, FACE1, RSDM1, STE24, FACE-1, Ste24p, ZMPSTE24