RSK2 / RPS6KA3 Rabbit mAb

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). Synonyma: CLS, RSK, HU-3, RSK2, MRX19, ISPK-1, XLID19, p90-RSK2, pp90RSK2, MAPKAPK1B, S6K-alpha3, RSK2 / RPS6KA3