ALKBH5 Rabbit mAb

Enables mRNA N6-methyladenosine dioxygenase activity. Involved in RNA metabolic process, mRNA export from nucleus, and response to hypoxia. Located in Golgi apparatus, cytosol, and nuclear speck.ALKBH5, also named as ABH5 and OFOXD1, is a Dioxygenase that demethylates RNA by oxidative demethylation. It is a mammalian demethylase that oxidatively reverses m6A in mRNA in vitro and in vivo. ALKBH5 is required for spermatogenesis. Synonyma: ABH5, OFOXD, OFOXD1, ALKBH5