CD116/GM-CSFRα Rabbit mAb

The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. Synonyma: GMR, CD116, CSF2R, SMDP4, CDw116, CSF2RX, CSF2RY, GMCSFR, CSF2RAX, CSF2RAY, alphaGMR, GMR-alpha, GMCSFR-alpha, GM-CSF-R-alpha, CD116/GM-CSFRα