[KD Validated] TOLLIP Rabbit mAb

This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene. Synonyma: TOLLIP, IL-1RAcPIP, toll-interacting protein