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Irf3 Rabbit pAb

Irf3 Rabbit pAb
Poznámka k dopravě
Dopravné k jednorázové objednávce činí 2.000 Kč, které rozpočítáváme při fakturaci do cen za zboží. V rámci snížení nákladů na dopravu se snažíme konsolidovat objednávky tak, aby se tato suma rozdělila mezi maximum zákazníků. Před objednáním u dodavatele jsou všichni zákazníci vždy předem informovaní o aktuální výši dopravy.
Irf3 Rabbit pAb
Mediates interferon-stimulated response element (ISRE) promoter activation. Functions as a molecular...
3 136,00Kč
Cena bez DPH: 2 591,74Kč
  • Výrobce: ABclonal
  • Kód výrobce: ABC-A24864

Dostupné možnosti

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Dotaz na zboží

Mgr. Lenka Šídová (Kasalová)

Produktový specialista - Buněčná biologie (ext.)

Mediates interferon-stimulated response element (ISRE) promoter activation. Functions as a molecular switch for antiviral activity. DsRNA generated during the course of an viral infection leads to IRF3 phosphorylation on the C-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of genes under the control of ISRE. The complex binds to the IE and PRDIII regions on the IFN-alpha and IFN-beta promoters respectively. IRF-3 does not have any transcription activation domains. Synonyma: IRF-3,IIAE7,IRF 3
Technické specifikace
Doprava a skladování Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Vlastnosti
Aplikace WB,IHC-P,ELISA
Fluorochrom Unconjugated
Klon Polyclonal Antibodies
Předpokládaná křížová reaktivita Human,Mouse,Rat
Původ Rabbit
Specifita Mouse
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