ABflo® 488 Rabbit anti-Mouse CD126/IL-6Rα chain mAb

Enables interleukin-6 binding activity and interleukin-6 receptor activity. Involved in T-helper 17 cell lineage commitment and interleukin-6-mediated signaling pathway. Located in cell surface. Part of interleukin-6 receptor complex. Is expressed in several structures, including adipose tissue, alimentary system, genitourinary system, hemolymphoid system, and nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease, Huntington's disease, hyper IgE syndrome, obesity, and stomach cancer. Orthologous to human IL6R (interleukin 6 receptor). Synonyma: Il6r, CD126, IL-6R, IL-6RA, IL-6R-alpha