RIP3 Rabbit mAb

Enables NF-kappaB-inducing kinase activity and protein serine/threonine kinase activity. Involved in several processes, including execution phase of necroptosis, hematopoietic or lymphoid organ development, and regulation of programmed cell death. Acts upstream of or within several processes, including I-kappaB kinase/NF-kappaB signaling, positive regulation of intrinsic apoptotic signaling pathway, and positive regulation of protein deacetylation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system, hemolymphoid system gland, male reproductive gland or organ, primitive streak, and turbinate bone primordium. Orthologous to human RIPK3 (receptor interacting serine/threonine kinase 3). Synonyma: Rip3, 2610528K09Rik