[KO Validated] CD47 Rabbit mAb

Predicted to enable protein binding activity involved in heterotypic cell-cell adhesion and thrombospondin receptor activity. Involved in positive regulation of activation-induced cell death of T cells, regulation of nitric oxide biosynthetic process, and regulation of synapse pruning. Acts upstream of or within several processes, including monocyte aggregation, opsonization, and positive regulation of phagocytosis. Located in extracellular exosome and plasma membrane. Is active in glutamatergic synapse and presynapse. Is expressed in several structures, including alimentary system, central nervous system, genitourinary system, hemolymphoid system gland, and liver and biliary system. Orthologous to human CD47 (CD47 molecule). Synonyma: IAP, Itgp, 9130415E20Rik, B430305P08Rik