[KO Validated] ATG16L1 Rabbit mAb

The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene. Synonyma: IBD10, WDR30, APG16L, ATG16A, ATG16L, ATG16L1