DHRS9 Rabbit pAb

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. Synonyma: RDHL, RDH15, RDHTBE, SDR9C4, RDH-TBE, RETSDR8, hRoDH-E2, 3ALPHA-HSD, 3-alpha-HSD, DHRS9