DNAJB6 Rabbit pAb

This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants, however, not all variants have been fully described. Synonyma: DJ4, MRJ, DnaJ, HSJ2, HHDJ1, HSJ-2, MSJ-1, LGMD1D, LGMD1E, LGMDD1, DNAJB6