COMMD1 Rabbit pAb

Enables several functions, including phosphatidylinositol-3,4-bisphosphate binding activity, phospholipid binding activity, and protein homodimerization activity. Involved in several processes, including Golgi to plasma membrane transport, negative regulation of protein localization to cell surface, and regulation of cellular protein metabolic process. Acts upstream of or within negative regulation of NF-kappaB transcription factor activity. Located in cytosol, endosome, and nucleoplasm. Part of Cul2-RING ubiquitin ligase complex. Synonyma: MURR1, C2orf5, COMMD1