EPAS1/HIF2α Rabbit pAb

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. Synonyma: HLF, MOP2, ECYT4, HIF2A, PASD2, bHLHe73, EPAS1/HIF2α