FAM65B Rabbit pAb

This gene encodes an atypical inhibitor of the small G protein RhoA. Inhibition of RhoA activity by the encoded protein mediates myoblast fusion and polarization of T cells and neutrophils. The encoded protein is a component of hair cell stereocilia that is essential for hearing. A splice site mutation in this gene results in hearing loss in human patients. Synonyma: PL48, DFNA21, DIFF40, DIFF48, FAM65B, MYONAP, C6orf32, DFNB104