Phospho-PEA15-S104 Rabbit pAb

This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. Synonyma: PED, MAT1, HMAT1, MAT1H, PEA-15, HUMMAT1H, PED-PEA15, PED/PEA15, Phospho-PEA15-S104