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Human Integrin alpha 4 Monoclonal Antibody, Endotoxin 0.05 EU/mg

Human Integrin alpha 4 Monoclonal Antibody, Endotoxin 0.05 EU/mg
Poznámka k dopravě
Dopravné k jednorázové objednávce činí 2.000 Kč, které rozpočítáváme při fakturaci do cen za zboží. V rámci snížení nákladů na dopravu se snažíme konsolidovat objednávky tak, aby se tato suma rozdělila mezi maximum zákazníků. Před objednáním u dodavatele jsou všichni zákazníci vždy předem informovaní o aktuální výši dopravy.
Human Integrin alpha 4 Monoclonal Antibody, Endotoxin 0.05 EU/mg
Natalizumab is a monoclonal anti-integrin antibody which binds to the alpha 4 subunit of integrins t...
48 555,00Kč
Cena bez DPH: 40 128,10Kč
  • Výrobce: ABclonal
  • Kód výrobce: ABC-YR0129

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Dotaz na zboží

Mgr. Lenka Šídová (Kasalová)

Produktový specialista - Buněčná biologie (ext.)

Natalizumab is a monoclonal anti-integrin antibody which binds to the alpha 4 subunit of integrins to prevent migration of immune cells, and is used to treat Crohn's disease or multiple sclerosis.Humanized IgG4k monoclonal antibody produced in murine myeloma cells. Natalizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to a4-integrin.Binds to the α4-subunit of α4b 1 and α4b 7 integrins expressed on the surface of all leukocytes except neutrophils, and inhibits the α4-mediated adhesion of leukocytes to their counter-receptor(s). Synonyma: ITGA4, IA4, CD49D
Technické specifikace
Doprava a skladování Store at 2 - 8℃. 2 - 8°C for up to 4 weeks and -80°C for long term storage (Avoid repeated freezing and thawing)
Vlastnosti
Aplikace ELISA,neutralization,functional assays such as bioanalytical PK and ADA assays,and those assays for studying biological pathways
Fluorochrom <5% Determined by SECP
Klon Biosimilar
Předpokládaná křížová reaktivita <0.05EU/mg (<0.00005EU/μg) Determined by LAL gel clotting assay
Původ 0.2 μm filtration
Specifita Natalizumab Biosimilar
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