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In Vivo Grade Recombinant Anti-mouse PD-1 Rat IgG2a Kappa Monoclonal Antibody (Clone RMP1-14.1)

In Vivo Grade Recombinant Anti-mouse PD-1 Rat IgG2a Kappa Monoclonal Antibody (Clone RMP1-14.1)
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In Vivo Grade Recombinant Anti-mouse PD-1 Rat IgG2a Kappa Monoclonal Antibody (Clone RMP1-14.1)
The rat anti-mouse PD-1 monoclonal antibody (clone No. RMP1-14, rat IgG2a kappa) reacts with the mou...
5 401,00Kč
Cena bez DPH: 4 463,64Kč
  • Výrobce: ABclonal
  • Kód výrobce: ABC-YR0292

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Mgr. Lenka Šídová (Kasalová)

Produktový specialista - Buněčná biologie (ext.)

The rat anti-mouse PD-1 monoclonal antibody (clone No. RMP1-14, rat IgG2a kappa) reacts with the mouse PD-1 protein (CD279 or programmed death-1) encoded by the mouse pdcd1 gene, a member of the CD28 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2, both of which belong to the B7 family. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD 1 antibody and the anti-mouse PD L1 antibody which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The RMP1-14 antibody blocks the binding of both the mouse PD-L1 protein and the mouse PD-L2 protein to the mouse PD-1 protein. Synonyma:
Technické specifikace
Doprava a skladování Store at 2 - 8℃. 2 - 8°C for up to 4 weeks and -80°C for long term storage (Avoid repeated freezing and thawing)
Vlastnosti
Aplikace immunohistochemistry (IHC),Flow Cytometry (FC),and various in vitro and in vivo functional assays.
Fluorochrom <5% Determined by SECP
Klon Biosimilar
Předpokládaná křížová reaktivita <1EU/mg (<0.001EU/μg)Determined by LAL gel clotting assay
Původ 0.2 μm filtration
Specifita RMP1-14.1
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