Anti-mGluR2/3 Antibody

mGluR2/3 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat mGluR2/3 and is antigen affinity purified. It is great for use in WB, IHC. Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.