CD68 iFluor488

The clone KP1 recognizes 110 kDa highly glycosylated lysomal-associated membrane protein (LAMP) known as CD68. It plays important role in the immune process of endocytosis and/or lysosomal trafficking mostly carried out by cellular components of innate immunity. The CD68 is abundantly expressed in the cytoplasmic granules of macrophages, monocytes, neutrophils, basophils, subset of hematopoietic progenitors, γ/δ T cells, NK cells, LAK cells, subset of B cells, fibroblasts, and endothelial cells. Studies suggest that KP1 is a very useful tool for studying disorders of the monocyte/macrophage system, including both reactive and neoplastic states.