HEK293-FAP

Disclaimer: The prices displayed for cell lines are exclusively for not-for-profit customers. If you represent a commercial entity, please contact us for alternative pricing.The HEK293-FAP cell line is a stable recombinant HEK293 cell line engineered to express the Fibroblast Activation Protein (FAP) at a high level, approximately 123,000 molecules per cell. This cell line was developed using inscreenex's landing pad technology, ensuring precise and reproducible integration of the FAP gene at a specific, pre-validated genomic locus. FAP, also known as Seprase or DPPIV, is a serine protease involved in the remodeling of the extracellular matrix, which is particularly important in processes such as wound healing, tissue repair, and fibrosis. FAP is also highly upregulated in the stroma of many epithelial cancers, making it a valuable target for oncology research and a potential biomarker for cancer-associated fibroblasts.The expression of FAP in this cell line was confirmed using flow cytometry with a target-specific antibody, ensuring consistent and reliable receptor density across the cell population. Transformed cell lines, Fetal Kidney, Growth Conditions: Monolayer, adherent, Biosafety level: BSL 1