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Anti-DGCR8 (Ser377) Antibody

Anti-DGCR8 (Ser377) Antibody
Poznámka k dopravě
Dopravné k jednorázové objednávce činí 2.500 Kč, které rozpočítáváme při fakturaci do cen za zboží. V rámci snížení nákladů na dopravu se snažíme konsolidovat objednávky tak, aby se tato suma rozdělila mezi maximum zákazníků. Před objednáním u dodavatele jsou všichni zákazníci vždy předem informovaní o aktuální výši dopravy.
Anti-DGCR8 (Ser377) Antibody
The Drosha-DGCR8 microprocessor complex is required for microRNA (miRNA) biogenesis. DGCR8 (DiGeorge...
4 596,00Kč
Cena bez DPH: 3 798,35Kč

Dostupné možnosti

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Dotaz na zboží

Ondřej Hovorka Ph.D.

Výkonný ředitel

The Drosha-DGCR8 microprocessor complex is required for microRNA (miRNA) biogenesis. DGCR8 (DiGeorge Syndrome Critical Region 8) recognizes the RNA substrate, whereas Drosha functions as the endonuclease. DGCR8, which contains two double-stranded RNA (dsRNA)-binding domains, interacts with the pri-miRNA and functions as the molecular anchor that measures the distance from the ds-RNA-ssRNA junction and directs Drosha cleavage 11bp away (Han, J., et al, 2006). The efficiency of Drosha cleavage increases in the presence of heme and promotes the formation of highly ordered DGCR8 structures upon binding to RNA (Faller, M., et al, 2010).
Technické specifikace
Doprava a skladování Blue Ice
Vlastnosti
Aplikace WB
Izotyp IgG
Klon Polyclonal
Původ Rabbit
Specifita Human
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