CD79b APC

The clone CB3-1, a mouse monoclonal antibody recognizes a 37-39 kD type I integral membrane protein known as CD79. CD79 is a heterodimeric molecule comprised of an alpha-chain (CD79a) and a beta-chain (CD79b). It is noncovalently associated with the CD79a and cell surface IgM to form the B-cell receptor (BCR) complex. CD79b expression is exclusive to B lymphocytes and B cell lymphomas. It can be expressed either in the cytoplasm or on the cell surface depending on the maturation state of the B cells. The CD79 receptor complex triggers numerous signaling pathways to mediate B cell development, maintenance, and activation.