Activator protein 2 (AP-2/TFAP2A) Rabbit pAb

The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene. Synonyma: AP-2, BOFS, AP2TF, TFAP2, AP-2alpha, Activator protein 2 (AP-2/TFAP2A)