cIAP2 Rabbit pAb

This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. Synonyma: AIP1, API2, MIHC, CIAP2, HAIP1, HIAP1, IAP-1, MALT2, RNF49, c-IAP2, cIAP2