EXOSC1 Rabbit pAb

This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. Synonyma: p13, CSL4, SKI4, Csl4p, PCH1F, Ski4p, CGI-108, EXOSC1