CHAMP1 Rabbit pAb

This gene encodes a zinc finger protein that functions as a regulator of chromosome segregation in mitosis. The encoded protein is required for correct alignment of chromosomes on the metaphase plate, and plays a role in maintaining the attachment of sister kinetochores to microtubules from opposite spindle poles. Mutations in this gene are associated with an autosomal dominant form of intellectual disability. Synonyma: CAMP, CHAMP, MRD40, ZNF828, C13orf8, NEDHILD, CHAMP1