MED25 Rabbit pAb

This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. Synonyma: P78, ACID1, ARC92, BVSYS, PTOV2, CMT2B2, TCBAP0758, MED25