C5AR1 Rabbit pAb

Enables G protein-coupled receptor activity and complement component C5a receptor activity. Involved in several processes, including complement component C5a signaling pathway, mRNA transcription by RNA polymerase II, and positive regulation of ERK1 and ERK2 cascade. Located in apical part of cell and basolateral plasma membrane. Biomarker of Alzheimer's disease, asthma, chronic obstructive pulmonary disease, rhinitis, and severe acute respiratory syndrome. Synonyma: C5A, C5AR, C5R1, CD88, C5AR1