CC2D1A Rabbit mAb

This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in a nonsyndromic form of cognitive disability (MRT3). Synonyma: Lgd2, MRT3, TAPE, Aki-1, FREUD-1, Freud-1/Aki1, CC2D1A