Proteinase 3/PR3 Rabbit mAb

Enables enzyme binding activity, serine-type endopeptidase activity, and signaling receptor binding activity. Involved in several processes, including mature conventional dendritic cell differentiation, membrane protein ectodomain proteolysis, and neutrophil extravasation. Located in azurophil granule lumen, cytosol, and plasma membrane raft. Colocalizes with plasma membrane. Synonyma: MBN, MBT, NP4, P29, PR3, ACPA, AGP7, NP-4, PR-3, CANCA, C-ANCA, Proteinase 3/PR3