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Pan-Crotonyl-K Rabbit pAb

Pan-Crotonyl-K Rabbit pAb
Poznámka k dopravě
Dopravné k jednorázové objednávce činí 2.000 Kč, které rozpočítáváme při fakturaci do cen za zboží. V rámci snížení nákladů na dopravu se snažíme konsolidovat objednávky tak, aby se tato suma rozdělila mezi maximum zákazníků. Před objednáním u dodavatele jsou všichni zákazníci vždy předem informovaní o aktuální výši dopravy.
Pan-Crotonyl-K Rabbit pAb
Lysine crotonylation (Kcr) was first discovered about 10 years ago, as a PTM of histone. It was reve...
3 427,00Kč
Cena bez DPH: 2 832,23Kč
  • Výrobce: ABclonal
  • Kód výrobce: ABC-A20502

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Dotaz na zboží

Mgr. Lenka Šídová (Kasalová)

Produktový specialista - Buněčná biologie (ext.)

Lysine crotonylation (Kcr) was first discovered about 10 years ago, as a PTM of histone. It was revealed that Kcr is an evolutionarily conserved and common PTM that occurs in both core histone and some non-histone proteins in a variety of organisms. Similar to other types of PTM, Kcr is a reversible modification. The classic histone acetyltransferases (HATs), p300/CBP, PCAF, and MOF, are responsible for most crotonylation events, while the histone deacetylases (HDACs) HDAC1/2/3 and SIRT1/2/3 reverse these reactions . The chromodomain protein CDYL acts as a crotonyl-CoA hydratase to negatively regulate histone Kcr by reducing substrate supply. CDYL-regulated Kcr of RPA1 plays an important role in homologous recombination (HR)-mediated DNA repair (23), while HDAC-regulated histone crotonylation is reduced after DNA damage . Synonyma:
Technické specifikace
Doprava a skladování Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Vlastnosti
Aplikace WB,ELISA
Fluorochrom Unconjugated
Klon Other Modified Antibodies
Předpokládaná křížová reaktivita Human,Mouse,Rat
Původ Rabbit
Specifita Human
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