[KD Validated] NUR77 Rabbit mAb

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. Synonyma: HMR, N10, TR3, NP10, GFRP1, NAK-1, NGFIB, NUR77, [KD Validated] NUR77