ASC/TMS1 Rabbit mAb

Enables identical protein binding activity and protein dimerization activity. Involved in several processes, including activation of cysteine-type endopeptidase activity, positive regulation of cytokine production, and regulation of defense response. Acts upstream of or within several processes, including defense response to Gram-positive bacterium, positive regulation of macromolecule metabolic process, and regulation of autophagy. Located in cytosol, extracellular region, and nucleus. Part of inflammasome complex. Is expressed in several structures, including alimentary system, brain, heart, hemolymphoid system gland, and urinary system. Orthologous to human PYCARD (PYD and CARD domain containing).