B7-H4 / B7S1 / B7x Rabbit pAb

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. Synonyma: VTCN1, B7-H4, B7H4, B7S1, B7X, B7h.5, PRO1291, VCTN1, V-set domain-containing T-cell activation inhibitor 1, B7-H4 / B7S1 / B7x