ABflo® 488 Rabbit anti-Human MERTK mAb

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). Synonyma: MERTK, MER, RP38, Tyro12, c-Eyk, c-mer, tyrosine-protein kinase Mer